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apl. Prof. Dr. Helmut Rosemeyer - Publikationen

Organische Materialchemie -
Bioorganische Chemie
Institut für Chemie neuer Materialien
Universität Osnabrück
Barbarastraße 7
D-49069 Osnabrück

Referierte Manuskripte

  1. Analytische Aspekte der Koordinationsreaktionen des Hexamethylphosphorsäuretriamids in wässrigen Lösungen. M. Ziegler, H. Rosemeyer, H. Winkler und G. Modzel, Talanta, 1976, 23, 718 - 721.

  2. 5-Azido-w-bromo-2-nitroacetophenone - A Crosslinking Reagent with Groups of Selective Reactivity. F. Seela and H. Rosemeyer, Hoppe-Seyler's Z. Physiol. Chem., 1977, 358, 129.

  3. Substrate- and Product-Affinity Resins for Adenosine Deaminase Obtained by Immobilisation of Adenosine and Inosine via 2',3'-Cyclic Acetal Derivatives. H. Rosemeyer und F. Seela, Carbohydr. Res., 1978, 62, 155.

  4. Immobilisierung von Cytidin und Uridin über 2',3'-O-cyclische Acetalderivate an Agarose. F. Seela und H. Rosemeyer, Z. Naturforsch., 1978, 33c, 56.

  5. Immobilisation of Tubercidin and Nebularine via 2',3'-Cyclic Acetals: Biospecific and Non-specific Interactions of Affinity Resins with Adenosine Deaminase. H. Rosemeyer und F. Seela, Carbohydr. Res., 1979, 74, 117.

  6. Immobilisierung von Adenosinacetalen mit variablem Alkylidenrest - die Funktion des Spacers bei enzymatischer Desaminierung. F. Seela, J. Ott und H. Rosemeyer, Z. Naturforsch., 1979, 34c, 350.

  7. Polymer-Linked 6-Azauridine-5'-Monophosphate - A Resin of High Bioaffinity to Orotidine-5'-phosphate Decarboxylase. H. Rosemeyer and F. Seela, J. Med. Chem., 1979, 22, 1545.

  8. Immobilisierte Ribonucleoside - Ihre Synthese und Bioaffinität. Helmut Rosemeyer, Dissertation 1980, Universität-GH Paderborn.

  9. Immobilisation of Nucleoside Antimetabolites to Polymer Resins and Their Interaction with Adenosine Deaminase. F. Seela, H. Rosemeyer und J. Ott in Enzyme Inhibitors, U. Brodbeck (Eds.), Verlag Chemie, 1980, 201.

  10. Agarose-linked Xanthosine: A Biospecific Resin for Guanine Aminohydrolase. H. Rosemeyer and F. Seela, Carbohydr. Res., 1981, 90, 53.

  11. Quantitative Affinity Chromatography of Adenosine Deaminase on Polymer-Bound Inosine: The Assessment of Binding Constants by Biospecific Elution. H. Rosemeyer and F. Seela, Anal. Biochem., 1981, 115, 339.

  12. Adenosine Deaminase Covalently Linked to Soluble Dextran - The Effect of Immobilization on Thermodynamic and Kinetic Parameters. H. Rosemeyer, E. Körnig and F. Seela, Eur. J. Biochem., 1982, 122, 375.

  13. Dextran-Linked Purine Nucleosides as Substrates and Inhibitors of Adenosine Deaminase. H. Rosemeyer, E.Körnig and F. Seela, Eur. J. Biochem., 1982, 127, 185.

  14. Methylated 7-Deazahypoxanthines as Regiochemical Probes of Xanthine Oxidase. H. Rosemeyer and F. Seela, Eur. J. Biochem., 1983, 134, 513.

  15. Dextran-Bound Purine Nucleosides as Substrates and Inhibitor of Adenosine Deaminase. H. Rosemeyer und F. Seela in “Affinity Chromatography and Biological Recognition“ (I. M. Chaiken, M. Wilchek und I. Parikh, Eds.) Academic Press, New York, 1983.

  16. Polymer-linked Acycloguanosine. H. Rosemeyer and F. Seela, Makromol. Chem., 1984, 185, 687.

  17. Isomeric N-Methyl-7-deazaguanines: Synthesis, Structural Assignment, and Inhibitory Activity on Xanthine Oxidase. F. Seela, W. Bussmann, A. Götze and H. Rosemeyer, J. Med. Chem., 1984, 27, 981.

  18. Dextran-verknüpftes N6-(2-Isopentenyl)adenosin- ein polymergebundener Antimetabolit mit „Sollbruchstelle“. H. Rosemeyer und F. Seela, Angew. Chem., 1984, 96, 365.

  19. Spontaneous Hydroxylation of a Cyclization Intermediate of Allopurinol. H. Rosemeyer, K. Kaiser and F. Seela, J. Org. Chem., 1985, 50, 1847.

  20. Spontane Öffnung des Pyrimidinringes in Pyrrolo[2,3-d]pyrimidinen nach intramolekularer Acylierung. H. Rosemeyer, K. Kaiser, F. Seela, V. Zabel und W. Saenger, Helv. Chim. Acta, 1985, 68, 534.

  21. Ein Nucleolipid mit dem antiviralen Acycloguanosin als Kopfgruppe - Synthese und Liposomenbildung. H. Rosemeyer, M. Ahlers, B. Schmidt und F. Seela, Angew. Chem., 1985, 97, 500.

  22. A Nucleolipid with Antiviral Acycloguanosine as Head Group - Synthesis and Liposome Formation. H. Rosemeyer, M. Ahlers, B. Schmidt and F. Seela, Angew. Chem., Int. Ed., 1985, 24, 501.

  23. Hydrolytic Cleavage of 6-Oxopurines After Intramolecular Acylation at N-3. H. Rosemeyer and F. Seela, Heterocycles, 1985, 23, 2669.

  24. Cyclisation of 7-Deazaxanthine-9-propionic Acid to an Active-Site-Directed, Irreversibly Acting Inhibitor of Xanthine Oxidase. H. Rosemeyer, U. Kretschmer and F. Seela, Helv. Chim. Acta, 1985, 68, 2165.

  25. Spontaneous Hydroxylation after Intramolecular Cyclisation of 9-[2-(Carboxyethyl)]-hypoxanthine and Isosteres Thereof. H. Rosemeyer, K. Kaiser, U. Kretschmer and F. Seela in “Bioorganic Heterocycles“ (H. C. van der Plas, M. Simonyi, F. C. Alderweireldt, J. A. Lepoivre, Eds.), Elsevier, Amsterdam, 1986, 253.

  26. Synthesis and Application of Isosteric Purine 2'-Deoxyribofuranosides. F. Seela, U. Bindig, H. Driller, W. Herdeing, K. Kaiser, A. Kehne, H. Rosemeyer and H. Strecker, Nucleosides, Nucleotides, 1987, 6, 11.

  27. Dextran-linked 7-Deazaguanine - A Polymer-Bound Inhibitor of Xanthine Oxidase. H. Rosemeyer, K. Kaiser and F. Seela, Int. J. Bio. Macromol., 1987, 9, 205.

  28. 5-Aza-7-deaza-2'-deoxyguanosine: Studies on the Glycosylation of Weakly Nucleophilic Imidazo[1,2-a]-s-triazinyl Anions. H. Rosemeyer and F. Seela, J. Org. Chem., 1987, 52, 5136.

  29. 15N-NMR spectra of Wyosine and Related Ribonucleosides. B. Golankiewicz, W. Folkman, H. Rosemeyer and F. Seela, Nucleic Acids Res., 1987, 15, 9075.

  30. Synthesis of 5-Aza-7-deazapurine and 3,7-Dideazapurine 2'-Deoxyribofuranosides by Solid-Liquid Phase-Transfer Glycosylation. F. Seela, H. Rosemeyer and W. Bourgeois, Nucleic Acids Res., Symp. Ser., 1987, 18, 49.

  31. 7-Carbapurine Ribofuranosides: Synthesis by Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra. F. Seela, H. Rosemeyer, A. Biesewig and T. Jürgens, Nucleosides, Nucleotides, 1988, 7, 581.

  32. Stereoselective Synthesis of Pyrrolo-[2,3-d]pyrimidine a- and b-D-Ribonucleosides from Anomerically Pure D-Ribofuranosyl Chlorides: Solid-Liquid Phase-Transfer Glycosylation and 15N-NMR Spectra. H. Rosemeyer and F. Seela, Helv. Chim. Acta, 1988, 71, 1573.

  33. Pyrazolo[3,4-d]pyrimidine 2'-Deoxyribo- and 2',3'-Dideoxyribofuranosides: Synthesis and Application to Oligonucleotide Chemistry. F. Seela, H. Driller, K. Kaiser, H. Rosemeyer and H. Steker, Nucleosides, Nucleotides, 1989, 8, 789.

  34. Unambiguous Assignment of Anomeric Configuration of Nucleosides by NOE-Difference Spectroscopy. G. Toth, H. Rosemeyer and F. Seela, Nucleosides, Nucleotides, 1989, 8, 1091.

  35. Bending of Oligonucleotides Containing an Isosteric Nucleobase: 7-Deaza-2'-deoxyadenosine Replacing dA within d(A)6 - Tracts. F. Seela, H. Berg and H. Rosemeyer, Biochemistry, 1989, 28, 6193.

  36. Assignment of Anomeric Configuration of D-Ribo-, Arabino-, 2'-Deoxyribo-, and 2',3'-Dideoxyribonucleosides by NOE Difference Spectroscopy. H. Rosemeyer, G. Toth and F. Seela, Nucleosides, Nucleotides, 1989, 8, 587.

  37. 2', 3'-Dideoxy-3'-fluorotubercidin and Related Dideoxynucleosides: Synthesis via a 2'-Deoxy 3'-oxoribofuranoside Intermediate and Conformational Studies. H. Rosemeyer and F. Seela, Helv. Chim. Acta, 1989, 72, 1084.

  38. Facile Synthesis of Pyrrolo[2,3-d]pyrimidine and Pyrrolo[3,2-c]pyridine 2',3'-Dideoxyribonucleosides via Nucleobase Anion Glycosylation with 2,3-Dideoxy-D-glycero-pentofuranosyl Chloride. F. Seela, W. Bourgeois, H.-P. Muth, H. Rosemeyer, Heterocycles, 1989, 29, 2193.

  39. Syn-Anti Conformational Analysis of Regular and Modified Nucleosides by 1D 1H NOE Difference Spectroscopy: A Simple Graphical Method Based on Conformationally Rigid Molecules. H. Rosemeyer, G. Toth, B. Golankiewicz, Z. Kazimierczuk, W. Bourgeois, U. Kretschmer, H.-P. Muth and F. Seela, J. Org. Chem., 1990, 55, 5784.

  40. Orientation, Recognition, and Photoreaction of Nucleolipids in Model Membranes. M. Ahlers, H. Ringsdorf, H. Rosemeyer und F. Seela, Colloid Polym. Sci., 1990, 268, 132.

  41. Base-modified Purine 2'3'-Dideoxyribonucleoside 5'-Triphosphates: Selective Inhibitors of HIV Reverse Transcriptase. F. Seela, W. Bourgeois, R. Gumbiowski, A. Mertens, H.-P. Muth, A. Röling und H. Rosemeyer, in “Progress in  AIDS Research (Ed. M. Schauzu)“, MMV Medizin Verlag, München, 1990, 247.

  42. Base-Modified 2'-Deoxyribonucleosides in Bended DNA-Fragments: Differential Bending at 3'- and 5'-Junctions of H- and B-DNA. F. Seela, H. Rosemeyer and T. Grein, Nucleosides, Nucleotides, 1990, 9, 411.

  43. Configurational and Conformational Analysis of Regular and Modified Nucleosides by 1D-NOE Difference Spectroscopy. H. Rosemeyer and F. Seela, Nucleosides, Nucleotides, 1990, 9, 417.

  44. Determination of the Syn-Anti Equilibrium of Regular and Modified Nucleosides by 1D 1H-NOE-Spectroscopy. H. Rosemeyer and F. Seela, Collect. Czech. Chem. Commun., 1990, 55, 13.

  45. Synthesis of Indole, Indazole, and 3-Deazapurine 2'-Deoxy-ß-D-ribo- and 2',3'-Dideoxy-D-ribonucleosides. F. Seela, W. Bourgeois, H. Rosemeyer and T. Grein, Collect. Czech. Chem. Commun., 1990, 55, 37.

  46. Base-Modified Purine 2',3'-Dideoxyribonucleosides: Synthesis via Deoxygenation or Direct Nucleobase Anion Glycosylation. F. Seela, H. Rosemeyer, R. Gumbiowski, K. Mersmann, H.-P. Muth, and A. Röling, Nucleosides, Nucleotides, 1991, 10, 409.

  47. Synthesis of 3-Deaza-2'-deoxyadenosine and 3-Deaza-2',3'-dideoxyadenosine: Glycosylation of the 4-Chloroimidazo[4,5-c]pyridinyl Anion. F. Seela, H. Rosemeyer and S. Fischer, Helv. Chim. Acta, 1990, 73 (6), 1602.

  48. Oligonucleotides with Modified Bases or Altered Sugar-Phosphate Backbone. F. Seela, H. Rosemeyer, T. Grein, A. Röling, and R. Mertens, 1991.

  49. (2-Deoxy-ß-D-xylofuranosyl)thymine Building  Blocks for Solid-Phase Synthesis and Properties of Oligo(2'-Deoxyxylonucleotides). H. Rosemeyer and F. Seela, Helv. Chim. Acta, 1991, 74, 748.

  50. Solid-Phase Synthesis of Oligo(2'-deoxyxylonucleotides) and PCR-Amplification of Base-Modified DNA-Fragments. F. Seela, H. Rosemeyer, M. Krecmerovà and A. Röling, Nucleic Acids Res., Symposium Series, 1991, 24, 87.

  51. (2'-Deoxy-ß-D-xylofuranosyl)adenine Building Blocks for Solid-Phase Synthesis and Properties of Oligo(2'-deoxyxylonucleotides). H. Rosemeyer, M. Krecmerova and F. Seela, Helv. Chim. Acta, 1991, 74, 2054.

  52. Formation of an Unexpected 2-Deoxy-α-D-Threo-pentofuranosyl Azide by Reaction of O2,3’-anhydro-5'-O-trityl-2'-deoxycytidine with Lithium Azide. I. A. Mikailopulo, G. V. Zaitseva, E. V. Vaaks and H. Rosemeyer, F. Seela, Nucleosides, Nucleotides, 1992, 11, 273.

  53. Structure of Lumazine N1(2'-Deoxy-D-ribonucleosides (=1-(2’-Deoxy-D-ribofuranosyl)peridine-2,4(1H,3H)-diones): A Revision of the Anomeric Configuration. X. Cao, W. Pfleiderer, H. Rosemeyer, F.Seela, W. Bannwarth and P. Schönholzer, Helv. Chim. Acta, 1992, 75,1267.

  54. 2'-Deoxy-β-D-xylothymidinyl-(3',5')-2'-deoxy-b-D-xylothymidylate: Stereochemical Course of Dinucleoside Phosphonate Formation and Conformational Properties, H. Rosemeyer, I. Strodtholz and F. Seela, Bioorg. Med. Chem.Lett., 1992, 2, 1201.

  55. 1-Deaza and 3-Deazapurines in the Reaction of Microbiological Transglycosylation, I.A. Mikhailopulo, A.I. Zinchenko, S.B. Bokut, N.V. Dudchik, V.N. Baraj, E.N. Kalinichenko, H. Rosemeyer and F. Seela, Biotechnol. Lett., 1992, 14, 885.

  56. Synthesis of 2'-Azido-2',3'-Didehydro 2',3'-Dideoxythymidine. A. Mikailopulo, G.V. Zaitseva, E.V. Vaaks, J. Balzarini, E. DeClercq, H. Rosemeyer, and F. Seela, Liebigs Ann., 1993, 513.

  57. Oligonucleotides Containing 2'-Deoxyxylocytidine. F. Seela, K. Wörner and H. Rosemeyer, Collect. Czech. Chem. Commun., 1993, 58, 150.

  58. Kernmagnetische Resonanz und chemische Verschiebung (NMR-Spektroskopie). H. Rosemeyer, in: D'Ans Lax, Springer Verlag, Berlin, 1994, pp 150f.

  59. 3-Deaza- and 7-Deazapurines: Duplex Stability of Oligonucleotides Containing Modified Adenine or Guanine Bases. T. Grein, S. Lampe, K. Mersmann, H. Rosemeyer, H. Thomas and F. Seela, Bioorg. Med. Chem. Lett., 1994, 4, 971.

  60. (2'-Deoxy-β-D-xylofuranosyl)cytosine: Base Pairing of Oligonucleotides with a Configurationally Altered Sugar-Phosphate Backbone. F. Seela, K. Wörner and H. Rosemeyer, Helv.Chim. Acta, 1994, 77, 883.

  61. Oligonucleotides with Unnatural Bases or an Altered Sugar-Phosphate Backbone. F. Seela, H. Debelak, H. Rosemeyer, H. Thomas, T. Wenzel and M. Zulauf, Nucleic Acids Res., Symposium Series, 1994, 31, 151.

  62. Synthesis and Photochemical Conversion of Oligonucleotides Containing 2-Chloro-2'-deoxyadenosine. N. Ramzaeva, H. Rosemeyer and F. Seela, Nucleosides, Nucleotides, 1995, 14, 947.

  63. Xylose-DNA: Sequence-Dependent Duplex Stability as Function of Backbone Configuration. H. Rosemeyer and F. Seela, Nucleosides, Nucleotides, 1995, 14, 1041.

  64. 1,5-Anhydrohexitol Oligonucleotides: Synthesis, Base Pairing, and Recognition by Regular Oligodeoxyribonucleotides and Oligoribonucleotides. Ch. Hendrix, H. Rosemeyer, I. Verheggen, F. Seela, A. Van Aerschot and P. Herdewijn, Chem. Eur. J., 1997, 3, 110.

  65. Synthesis of 1-Deazaadenosine Analogues of (2',5') ApApA. I. A. Mikhailopoulo, E. N. Kalinichenko, T. L. Podkopaeva, H. Rosemeyer, T. Wenzel and F. Seela, Nucleosides, Nucleotides, 1996, 15, 445.

  66. Synthesis of 4-Substituted Benzimidazole 2' Deoxyribonucleosides and Utility of the 4-Nitro Compound as Universal Base. F. Seela, W. Bourgeois, H. Rosemeyer and T. Wenzel, Helv. Chim. Acta, 1996, 79, 488.

  67. Conformational Analysis of 3'-Deoxyribonucleosides Using 1D-NOE Difference Spec-troscopy. A. Kumar, S.B. Katti, H. Rosemeyer and F. Seela, Nucleosides, Nucleotides, 1996, 15, 1595.

  68. The DNA-Stabilizing Nucleoside 7-Iodo-2’-deoxytubercidin: Its Structure in Solid State and in Solution. F. Seela, M. Zulauf, H. Rosemeyer and H. Reuter, J. Chem. Soc. Perkin Trans 2, 1996, 2373.

  69. Xylose-DNA: Comparison of the Thermodynamic Stability of Oligo(2'-deoxyxylonucleotide)- and Oligo(2'-deoxyribonucleotide) Duplexes. A. Schöppe, H.J. Hinz, H. Rosemeyer and F. Seela, Eur. J. Biochem., 1996, 239, 33-41.

  70. Xylose-DNA Containing the Four Natural Bases. F. Seela, M. Heckel and H. Rosemeyer, Helv. Chim. Acta, 1996, 79, 1451.

  71. Synthesis and Application of Novel Nucleoside Phosphates and Phosphoramidites Modified at the Base Moiety. F. Seela, Y. Chen, A. Melenewski, H. Rosemeyer and C. Wei, Acta Biochim. Pol., 1996, 43, 45.

  72. Stereoelectronic Effects of Modified Purines on the Sugar Conformation of Nucleosides and Fluorescence Properties. H. Rosemeyer, M. Zulauf, N. Ramzaeva, G. Becher, E. Feiling, K. Mühlegger, I. Münster, A. Lohmann and F. Seela, Nucleosides, Nucleotides, 1997, 16, 821.

  73. Steric and Stereoelectronic Effects of 7-Deazapurine Bases on the Sugar Conformation of 2'-Deoxynucleosides. H. Rosemeyer, N. Ramzaeva, M. Zulauf, H. Thomas, Y. Chen, C. Mittelbach and F. Seela, Nucleosides, Nucleotides, 1997, 16, 1447.

  74. 1',5'-Anhydrohexitol Oligonucleotides (HNA): Hybridization, Strand Displacement, and RNase H Inhibition. Ch. Hendrix, H. Rosemeyer, B. De Bouvere, A. Van Aerschot, F. Seela and P. Herdewijn, Chem Eur. J., 1997, 3, 1513.

  75. A 2'5'-Adenylate Trimer with a Positively Charged 2'(3')-Terminal 8-(4-Aminobutyl)aminoadenosine Residue: Synthesis, Conformation and Rnase. L Binding, I.A. Mikhailopulo, E.N. Kalinichenko, T. L. Podkopaeva, M. Kelve, M. Saarma, M. Y. Lidaks, H. Rosemeyer and F. Seela, Nucleosides, Nucleotides, 1997, 16, 1855.

  76. Stereoelectronic Effects of Modified Purine Bases on the Sugar Conformation of Nucleosides: Pyrrolo[2,3-d]pyrimidines. H. Rosemeyer and F. Seela, J. Chem. Soc.Perkin Trans. 2, 1997, 2341.

  77. 7-Nitro-7-deaza-2'-deoxyadenosine and 8-Methyl-7-deaza-2'-deoxyguanosine: Pyrrolo[2,3-d]pyrimidine Nucleosides with Different Sugar Conformations. F. Seela, H. Rosemeyer, M. Zulauf, Y. Chen, G. Kastner, and H. Reuter, Liebigs Ann./Receuil, 1997, 2525.

  78. PURINES. F. Seela, N. Ramzaeva, H. Rosemeyer, Houben-Weyl, Methods of Organic Synthesis, 1998, Vol. E9b, 304-550.

  79. Glycerol-Furcated Oligonucleotides: Synthesis and Aggregation. H. Rosemeyer, E. Feiling, W. Nierling and F. Seela, Nucleosides, Nucleotides, 1999, 18, 1563-1564.

  80. 8-Azaadenosine and its 2'-Deoxynucleoside: Synthesis and Oligonucleotide Base Pair Stability. F. Seela, I. Münster, U. Löchner, and H. Rosemeyer, Helv. Chim. Acta, 1998, 81, 1139.

  81. The α-D anomer of 5-aza-7-deaza-2’-deoxyguanosine. F. Seela, H. Rosemeyer, A. Melenewski, E.-M. Heithoff, H. Eickmeier, and H. Reuter, Acta Cryst., 2002, C58, 142-144.

  82. The High-Anti Conformation of 7-Halogenated 8-Aza-7-deaza-2'-deoxyguanosines: A Study of the Influence of Modified Bases on the Sugar Structure of Nucleosides. F. Seela, G. Becher, H. Rosemeyer, H. Reuter, G. Kastner, and I. A. Mikhailopulo, Helv. Chim. Acta, 1999, 82, 105.

  83. Synthesis and Pairing Properties of Oligonucleotides Containing 3-Hydro-4-hydromethyl-1-cyclohexanyl Nucleosides. Y. Maurinsh, H. Rosemeyer, R. Esnouf, A. Medvedovici, J. Wang, G. Ceulemans, E. Lescrinier, C. Hendrix, R. Busson, P. Sandra, F. Seela, A. van Aerschot, and P. Herdewijn, Chem.- Eur. J., 1999, 5, 2139.

  84. Fluorescent DNA: The Development of 7-Deazapurine Nucleoside Triphosphates Applicable for the Sequencing at the Single Molecule Level. F. Seela, E. Feiling, J. Gross, F. Hillenkamp, N. Ramzaeva, H. Rosemeyer and M. Zulauf, J. Biotechnol., 2001, 86, 269.

  85. 2-Aza-2'-deoxyadenosine: Synthesis, Base Pairing Selectivity and Stacking Properties of Oligonucleotides. T. Sugiyama, E. Schweinberger, Z. Kazimierczuk, N. Ramzaeva, H. Rosemeyer and F. Seela, Chem.- Eur. J., 2000, 6, 369.

  86. Synthesis, Base Pairing and Stacking Properties of Oligonucleotides Containing 2-Aza-2'-deoxyadenosine. F. Seela, T. Sugiyama, E. Schweinberger, and H. Rosemeyer, Collec. Czech. Chem. Soc., 1999, 2, 124.

  87. Symmetrically and Unsymmetrically Bridged Methylenebis(allopurinols): Synthesis of Dimeric Potential Anti-Gout Drugs. H. Rosemeyer, M. Anders, F. Seela. Molecules, 2007, 12, 563.

  88. D-Altritol Nucleic Acids (ANA): Hybridisation Properties, Stability, and Initial Structural Analysis. B. Allart, K. Khan, H. Rosemeyer, G. Schepers, C. Hendrix, K. Rothenbacher, F. Seela, A. Van Aerschot, P. Herdewijn, Chem.- Eur. J., 1999, 5, 2424-2431.

  89. Cyclohexene Nucleic Acids: Nuclease Stable Oligonucleotides that Activate RNAse H and Increase Duplex Stability with Complementary RNA. J. Wang, I. Luyten, B. Verbeure, C. Hendrix, H. Rosemeyer, F. Seela, A. Van Aerschot and P. Herdewijn, J. Am. Chem. Soc.,  2000, 122, 8595.

  90. Oligonucleotides Functionalized by Fluorescein and Rhodamin Dyes: Michael Addition of Methyl Acrylate to 2’-Deoxypseudouridine. N. Ramzaeva, H. Rosemeyer, P. Leonard, K. Mühlegger, F. Bergmann, H. von der Eltz and F. Seela, Helv. Chim. Acta, 2000, 83, 1108.

  91. Perspectives in Nucleoside and Nucleic Acid Chemistry. M.V. Kisakürek, H. Rosemeyer, (Eds.), 420 pages, John Wiley & Sons, New York, Weinheim, 2000.

  92. 5-Aza-7-deazapurines: Synthesis and Properties of Nucleosides and Oligonucleotides in Recent Advances in Nucleosides: Chemistry and Chemotherapy, F. Seela and H. Rosemeyer, D. Chu (Ed.), Elsevier  Amsterdam, 2002, 505-533.

  93. 7-Deaza-2’-deoxyxanthosine Dihydrate Forms Water-Filled Nanotubes with CHO Hydrogen Bonds. F. Seela, T. Wiglenda, H. Rosemeyer, H. Eickmeyer and H. Reuter, Ang. Chem., 2002, 41, 603-605.

  94. 5-Aza-7-deazaguanine DNA: Recognition and Strand Orientation of Oligonucleotides Incorporating Anomeric Imidazo[1,2-a]-s-triazine Nucleosides, F. Seela, S. Amberg, A. Melenewski and H. Rosemeyer, Helv. Chim. Acta, 2001, 84, 1996.

  95. Pyrophosphoryl Derivatives of 1-(2-Deoxy-3-O-phosphonomethyl-ß-and α-D-erythro-pentofuranosyl)thymine: Synthesis and Substrate Properties Towards some DNA Polymerases, I. A. Mikhailopulo, T. I. Kulak, O. V. Tkachenko, S. L. Sentyureva, L. S. Vikturova, H. Rosemeyer, and F. Seela, Nucleosides, Nucleotides & Nucleic Acids, 2000, 19, 1885.

  96. The Influence of Dangling Base-Modified Nucleotides on DNA Duplex Stability, H. Rosemeyer and F. Seela, Perkin Trans. 2, 2002 746-750; published on the web 6th March 2002.

  97. α-Homo-DNA and RNA Form a Parallel Oriented Non-A, Non-B Type Double Helical Structure, M. Froeyen, E. Lescrinier, L. Kerremans, H. Rosemeyer, F. Seela, B. Verbeure, I. Lagoja, J. Rozenski, A. Van Aerschoz, R. Busson  and Piet Herdewijn, Chem.- Eur. J., 2001, 7, 5183.

  98. Cyclohexene Nucleic Acids (CeNA) Form Stable Duplexes with RNA and Induce RNAse H Activity, J. Wang, B. Verbeure, I. Luyten, M. Froyen, C. Hendrix, H. Rosemeyer, F. Seela, A. Van Aerschot and Piet Herdewijn, Nucleosides, Nucleotides & Nucleic Acids, 2001, 20, 785.

  99. Oligonucleotides Incorporating 7-(Aminoalkynyl) 7-Deaza-2’-deoxyguanosines: Duplex Stability and Phosphodiester Hydrolysis by Exonucleases, H. Rosemeyer, N. Ramzaeva, E. Albertmann, E. Feiling and F. Seela, Bioconjugate Chem., 2002, 13, 1274.

  100. Hoogsteen Versus Watson Crick Base Pairing: Incorporation of 2-Substituted Adenine- and 7-Deazaadenine 2’-Deoxy-ß-D-ribonucleosides into Oligonucleotides. N. Ramzaeva, E. Feiling, Z. Kazimierczuk, F. Seela, H. Rosemeyer, Chemistry & Biodiversity, 2007, 12, 2725-2744.

  101. Selection of new sequence-selective unnatural dsDNA binding peptides using a gel retardation experiment for library analysis, P. Chaltin, E. Lescrinier, T. Lescrinier, J. Rozenski, C. Hendrix, H. Rosemeyer, R. Busson, A. Van Aerschot and P. Herdewijn, Helv. Chim. Acta., 2002, 85, 2258.

  102. Oligonucleotides Incorporating 7-(ϖ-Aminoalkyn-1-yl)-7-deaza-2'-deoxyguanosines: Duplex Stability and Phosphodiester Hydrolysis by Exonucleases, H. Rosemeyer, N. Ramzaeva, E.-M. Becker, E. Feiling and F. Seela, Nucleosides, Nucleotides, Nucleic Acids, 2003, 22, 1231.

  103. Single-stranded DNA: Replacement of Canonical by Base-Modified Nucleosides in the Minihairpin 5'-d(GCGAAGC) and Constructs with the Aptamer 5’-d(GGTTGGTGTGGTTGG). H. Rosemeyer, V. Mokrosch, A. Jawalekar, E.-M. Becker and F. Seela, Helv. Chim. Acta, 2004, 87, 536.

  104. The Chemodiversity of Purine as a Constituent of Natural Products. H. Rosemeyer, Chemistry & Biodiversity, 2004, 1, 1-41.

  105. Purines, in: Science of Synthesis, Vol. 16.17, F. Seela, N. Ramzaeva, H. Rosemeyer, Thieme Verlag Stuttgart, 2003, pp 945-1108.

  106. Novel DNA Nanoparticles and Networks. F. Seela, A. M. Javalekar, V. R. Sirivolu, H. Rosemeyer, Y. He, and P. Leonard, Nucleosides, Nucleotides and Nucleic Acids, 2005, 24, 855.

  107. L-Nucleosides Containing Modified Nucleobases. F. Seela, W. Lin, Z. Kazimierczuk, H. Rosemeyer, Y. He, V. Glacon, X. Peng, X. Ming, M. Andreijewska, A. Gorska, X. Zhang, and P. LaColla, Nucleosides, Nucleotides and Nucleic Acids, 2005, 24, 859.

  108. 1,N6-Etheno-7-deaza-2’-deoxyadenosine and Pyrrolo-C: Synthesis, Base Pairing and fluorescence properties of 7-Deazapurine Nucleosides and Oligonucleotides, F. Seela, E. Schweinberger, K. Xu, V. R. Sirivolu, H. Rosemeyer, E.-M. Becker, Tetrahedron, 2007, 63, 3471.

  109. Nucleolipids: Natural Occurance, Synthesis, Molecular Recognition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials. Helmut Rosemeyer, Chemistry & Biodiversity, 2005, 2, 977-1062.

  110. Comparative Conformational Analysis of Nucleosides by NMR, X-Ray, and Semi-Empirical Methods, I. A. Mikhailopulo, Y. A. Sokolov, J. He, P. Chittepu, H. Rosemeyer, F. Seela, Nucleosides, Nucleotides and Nucleic Acids, 2005, 24, 701.

  111. Synthesis and Properties of Oligonucleotides Containing 2,4-Dihydroxycyclohexyl Nucleosides. D. Bardiot, H. Rosemeyer, E. Lescrinier, J. Rozenski, A. Van Aerschot, and P. Herdewijn, Helv. Chim. Acta, 2005, 88, 3210.

  112. Conformational and Chiral Selection of Oligonucleotides, M. Froeyen, F. Morvan, J.-J. Vasseur, P. Nielsen, A. Van Aerschot, H. Rosemeyer, P. Herdewijn, Chemistry & Biodiversity, 2007, 4, 803.

  113. Nucleolipids as Potential Organogelators, H. Rosemeyer, E.-M. Stürenberg, P. Herdewijn, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 995-999.

  114. Interactions of Viologens with Nucleic Acid Tetrades, C. S. Asaftei, H. Rosemeyer, L. Walder, Langmuir, 2008, 24, 5641-5643.

  115. Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine. Natalya Ramzaeva, Helmut Rosemeyer, MolBank, 2007, 1, M522.

  116. Synthesis of 3-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propanoic acid – A Functionalized Base Derivative of the Nucleoside Antibiotic Tubercidin. Helmut Rosemeyer, MolBank, 2007, 4, M555.

  117. Analysis of Phenacylester-Derivatives of Fatty Acids From Human Skin Surface Sebum by Reversed Phase HPLC: The Chromatographic Mobility as a Function of Physico-Chemical Properties. Juliana Bodoprost, Helmut Rosemeyer, Int. J. Mol. Sci., 2007, 8, 1111-1124.

  118. Extraordinary Thermal Stability of Oligodeoxynucleotide Octamers Built-Up From Alternating 7-Iodo-7-Deazaguanine and 5-Iodocytosine Base Pairs – DNA Duplex Stabilization by Halogen Bonds? Natalya Ramzaeva, Henning Eickmeier, Helmut Rosemeyer, Chemistry & Biodiversity, 2014, 11, 532-541, doi: 10.1002/cbdv.201300300.

  119. Synthesis of 3-(4-Chloro-2-methoxy-7H-pyrrolo[2,3-d]-pyrimidin-7-yl)propanoic acid – An N(9)-Functionalized 7-Deazapurine. Helmut Rosemeyer, MolBank, 2009, M590.

  120. Synthesis and Crystal Structures of O-2’,3’ Cyclic Cyclopentanone and -hexanone Ketals of the Cytostatic 5-Fluorouridine. Edith Malecki, Fei Ye, Hans Reuter, and Helmut Rosemeyer* Helv. Chim. Acta, 2009, 92, 1923-1932.

  121. Synthesis and Crystal Structures of Two 9-(2-Bromoethyl)-Functionalized 7-Deazapurines. Simona Asaftei, Martin Reichelt, Hans Reuter, and Helmut Rosemeyer*, Helv. Chim. Acta, 2009, 92, 1944-1951.

  122. Towards the Synthesis of Inosine Building Blocks for the Preparation of Oligonucleotides with Hydrophobic Alkyl Chains Between the Nucleotide Units. Karl Köstler and Helmut Rosemeyer, Molecules, 2009, 14, 4326-4336.

  123. Nucleolipids of the Cytostatic 5-Fluorouridine: Synthesis, Lipophilicity and Acidic Stability. Edith Malecki and Helmut Rosemeyer, Helv. Chim. Acta, 2010, 93, 1500-1512.

  124. Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acid (dXNA): An Orthogonal Nucleic Acid Candidate. M. Maiti, V. Siegmund, M. Abramov, E. Lescrinier, H. Rosemeyer, M. Froeyen, A. Ramaswamy, A. Ceulemans, A. Marx, P. Herdewijn, Chemistry Eur. J., 2012, 18, 869-879.

  125. Specific DNA Duplex Formation at an Artificial Lipid Bilayer: Towards a New DNA Biosensor Technology. Emma Werz, Sergei Korneev, Malayko Montilla-Martinez, Richard Wagner, Roland Hemmler, Claudius Walter, Jörg Eisfeld, Karsten Gall, and Helmut Rosemeyer, Chemistry & Biodiversity, 2012, 9, 272.

  126. Nucleoterpenes of Thymidine and 2’-Deoxyinsoine – Synthons for a Biomimetic Lipophilization of Oligonucleotides. Karl Köstler, Emma Werz, Edith Malecki, Malayko Montilla-Martinez, and Helmut Rosemeyer, Chemistry & Biodiversity, 2013, 10, 39.

  127. Synthesis of Functionalized Lipids and Their Use For the Hydrophobization of Nucleosides. Sergei Korneev, Helmut Rosemeyer, Helv. Chim. Acta, 2013, 96, 201.

  128. Mitsunobu Reactions of 5-Fluorouridine with Terpenols - Synthesis of DNA Building Blocks for a Biomimetic Lipophilisation of Nucleic Acids. Edith Malecki, Christine Knies, Emma Werz, and Helmut Rosemeyer, Chemistry & Biodiversity, 2013, im Druck; doi: 10.1002(cbdv.201300107.

  129. Nucleolipids of the Cancerostatic 5-Fluorouridine: Synthesis, Adherence to Oligonucleotides, and Incorporation into Artificial Lipid Bilayers. Edith Malecki, Vanessa Ottenhaus, Emma Werz, and Helmut Rosemeyer, Chemistry & Biodiversity, 2014, 11, 217. doi: 10.1002/cbdv.201300127.

  130. Specific Lipo-DNA Duplex Formation at an Artificial Lipid Bilayer: Fluorescence Microscopy Upon SYBR Green Staining. Emma Werz, and Helmut Rosemeyer, Beilstein J. Org. Chem., 2014, accepted for publication.

  131. Immobilization of 5-Fluorouridine to Chitosan. Edith Malecki, R. Viere, and Helmut Rosemeyer, Chemistry & Biodiversity, 2013, 10, 1828, DOI: 10.1002/cbdv.201300025.

  132. Synthesis of 2’-Deoxythymidine-, Uridine, and 5-Methyluridine Nucleolipids: Tools for a Tuned Lipophilization of Oligonucleotides. E. Werz, R. Viere, Gina Gaßmann, Edith Malecki, S. Korneev, and H. Rosemeyer, Helv. Chim. Acta, 2013, 96, 872; doi: 10.1002/hlca.201200573.

  133. Synthesis of 5-Fluorouridine Nucleolipids Derivatives and Their Cytostatic/Cytotoxic Activity Against Human HT-29 Human Carcinoma Cells. E. Malecki, A. Farhat, G. A. Bonaterra, R. Kinscherf, and H. Rosemeyer, Chemistry & Biodiversity, 2014, 11, 217, doi: 10.1002/cbdv.201300219.

  134. Transdermal Transport of Nucleolipids and Lipo-Oligonucleotides by Iontophoresis. V. Ottenhaus., H. Rosemeyer, 2014, in preparation.

  135. Identification of nucleoside analogues as inducers of neuronal differentiation using human reporter cells. Katharina Raasch, Edith Malecki, Maria Siemann, Malayko Martinez, Jürgen Heinisch, Janine Müller, Lidia Bakota, Christian Kaltschmidt, Barbara Kaltschmidt, Helmut Rosemeyer, and Roland Brandt., 2014, Chem. Biol. Drug Dis., accepted for publication.

  136. Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside. Koen Nauwelaerts, Karen Vastmans, Matheus Froeyen, Veerle Kempeneers, Jef Rozenski, Helmut Rosemeyer,1 Arthur Van Aerschot, Roger Busson, Jeffrey C. Lacey, Ekaterina Efimtseva, Sergey Mikhailov, Eveline Lescrinier, and Piet Herdewijn*, Nucleic Acids Res., 2003, 31(23): 6758–6769. doi:10.1093/nar/gkg911.

  137. “Yeast mail” and more: A new method to hide encrypted messages within eukaryotic genomes. Helmut Rosemeyer, Achim Paululat, and Jürgen Heinisch, Chemistry & Biodiversity, 2014, accepted for publication, doi: 10.1002/cbdv.201400160.

  138. Cytostatic/cytotoxic effects of 5-fluorouridine nucleolipid derivatives on colon-, hepatocellular- and renal carcinoma cells. A. Farhat, E. Malecki, D. Röthlein, M. Wolf, J. Schmitt,  G. A. Bonaterra, H. Rosemeyer, and R. Kinscherf, Chemistry & Biodiversity, 2014, 11, 469. doi: 10.1002/cbdv.201300347.

  139. Terminal Lipophilization of a Unique DNA Dodecamer by Various Nucleolipid Head Groups: Their Incorporation into Artificial Lipid Bilayers – Kinetics and Stability. Emma Werz and Helmut Rosemeyer, 2014, in preparation.

  140. Incorporation of Lipophilic Single Strands with Different Nucleolipid Head Groups into an Artificial Lipid Bilayer. E. Werz, N. Brending, M. Könemann, and H. Rosemeyer, 2014-09-10, MPEG4 video, urn:nbn:de:gbv:700-2014091012807.

Nicht-Referierte Manuskripte

  • Neue Wege in der AIDS-Forschung, F. Seela und H. Rosemeyer, Magazin der Universität Osnabrück, Februar 1992, 15 - 17.

  • Macht Fettiges in Zukunft noch fett? H. Rosemeyer, WirtschaftsPOST (Hrgb.: WFO, Wirtschaftsförderung Osnabrück GmbH), 2009, 1, 7.

Patentschriften und Patentanmeldungen

  1. F. Seela, W. Bourgeois, R. Gumbiowski, A. Röling, H. Rosemeyer, A. Mertens, H. Zilch, B. König, E. Koch, „Purine Analogue Nucleoside and Nucleotide Compounds“, US Patent 5,446,139; 29. 08. 1995.

  2. K. Mühlegger, H. von der Eltz, F. Seela, H. Rosemeyer, „Oligo(2’-desoxyribonucleotide) und ihre Anwendung als Arzneimittel mit antiviraler Wirkung“, Europäisches Patent EP 0611373 B1, WO 92/21692; 10. 12. 1992.

  3. K. Mühlegger, H. von der Eltz, F. Seela, H. Rosemeyer, „C-Nucleoside Derivatives and Their Use in Nucleic Acid Detection“, Europäisches Patent, EP 0815 117 B1, 19. 09.1996.

  4. F. Seela, H. Rosemeyer, E. Schweinberger, D. Heindl, F. Bergmann, „2-Azapurine Compounds and Their Use“, Europäische Patentanmeldung, WO 01/16149 A2, vom 01. 03. 2001.

  5. F. Seela, E. Schweinberger, H. Rosemeyer, „Fluoreszierende Ethenonucleoside und Oligonucleotide mit hoher Stabilität“, Deutsche Offenlegungsschrift DE 10 2004 009 977 A1 vom 01.03.2004.

  6. H. Rosemeyer, „Nucleolipide und deren Verwendung, sowie Vorrichtungen zur Nucleinsäureanalytik“, Europäische Patentschrift EP 1 893 773 B1 vom 23.01.2013. sowie PCT-Anmeldung vom 22. Juni 2006 (Int. Aktenzeichen: PCT/EP2006/006013); United States Patent No. US7914991; Nucleolipids and use thereof, and devices for nucleic acid analysis. 29.03.2011.

  7. Helmut Rosemeyer, Edith Malecki, Sergei Korneev, Emma Werz, Karsten Gall, Reactive, lipophilic nucleoside building blocks for the synthesis of hydrophobic nucleic acids. Europäische Patentanmeldung, 28.09. 2012. EP12186576.0

  8. Helmut Rosemeyer, Edith Malecki, 5-Fluorouracil Derivatives, Europäische Patentanmeldung, 28.09.2012. EP12186564.6

  9. Helmut Rosemeyer, Edith Malecki, Colloid-bonded Medicinal Compounds, Europäische Patentanmeldung, 28.09.2012. EP12186555.4

Konferenzbeiträge

  1. H. Rosemeyer, Immobilisierte Nucleoside und ihre Anwendung in der Affinitätschromatographie, Max-Planck-Institut für Experimentelle Medizin, Göttingen, April 1977 (Vortrag).

  2. F. Seela, H. Rosemeyer, Synthese und Affinität polymergebundener Ribonucleosid-O-2’,3’-Acetale, Chemiedozententagung, Berlin, April 1978 (Vortrag).

  3. H. Rosemeyer, F. Seela, Dextran-Linked Purine Nucleosides - Substrate and Inhibitors of Adenosine Deaminase, 5th International Symposium on Affinity Chromatography and Biological Recognition, Annapolis, Maryland, USA, Juni 1983 (Poster).

  4. H. Rosemeyer, Funktionalisierung von 7-Desazaguanin und Allopurinol an Dextran T80 - Polymergebundene Inhibitoren der Xanthin Oxidase, Univ. Mainz, April 1984 (Vortrag).

  5. M. Ahlers, H. Rosemeyer, H. Ringsdorf, Synthese und Charakterisierung von Nucleolipiden - Selbstorganisation und Oberflächenwechselwirkungen, GDCh-Symposium - Makromolekulare Chemie, Mainz, September 1985 (Poster).

  6. H. Rosemeyer, F. Seela, Spontaneous Hydroxylation after Intramolecular Cyclization of 9-(2-Carboxyethyl)-hypoxanthine and Isosteres Thereof, 4th FECHEM Conference, Houthalen, Belgien, Mai 1986 (Poster).

  7. H. Rosemeyer, F. Seela, Configurational and Conformational Analysis of Regular and Modified Nucleosides by 1D-NOE Difference Spectroscopy, Int. Symposium on Analysis of Nucleosides, Nucleotides and Oligonucleotide Components, Antwerpen, Belgien, September 1989 (Poster).

  8. H. Rosemeyer, F. Seela, Determination of the Syn-Anti Equilibrium of Regular and Modified Nucleosides by 1D-NOE Spectroscopy, Eigth Symposium on the Chemistry of Nucleic Acid Components, Bechyne Castle, CSSR, September 1990 (Oral Communication).

  9. H. Rosemeyer, Konformationsanalyse modifizierter Nucleoside und Synthese von Oligo(2’-desoxyxylonucleotiden), Universität Frankfurt, 30. Januar 1991. (Vortrag).

  10. H. Rosemeyer, Oligo(2’-deoxyxylonucleotides) - Synthesis and Structural Speculations, University of Michigan, Ann Arbor, September 1991 (Lecture).

  11. H. Rosemeyer, Oligo(2’-desoxyxylonucleotide) - Synthese und Spekulationen über ihre Struktur, Max-Planck-Institut für Experimentelle Medizin, Göttingen, November 1991 (Plenarvortrag).

  12. H. Rosemeyer, F. Seela, A Thermodynamic Study on Oligo(2’-deoxyxylo-nucleotides), 10th International Round Table on Nucleic Acids, Park City, Utah, USA, September 1992 (Poster).

  13. H. Rosemeyer, Xylose-DNA - Synthesis and Structural Properties - An Evolutionary Alternative, Weißrussische Akademie der Wissenschaften, Minsk, Weißrussland, April 1993 (Lecture).

  14. H. Rosemeyer, Configurational and Conformational Analysis of Nucleosides by NOE Spectroscopy, Universität Antwerpen, Belgien, Januar 1994 (Lecture).

  15. H. Rosemeyer, Vorträge im Rahmen der Ringvorlesung „Supramolekulare Chemie“, Universität Osnabrück, Januar/Februar 1997
    a) Die Anfänge der supramolekularen Organischen Chemie: Einschlußverbindungen, Cyclodextrine und Kronenether.
    b) Moleküle ohne chemische Bindungen? Catenane, Rotaxane, Olympische Ringe, Mobius-Bänder, Catena-DNA.
    c) Dendrimere, Arborole, Kaskadenmoleküle, molekulare Pinzetten und molekulare Getriebe.

  16. H. Rosemeyer, Vortrag im Rahmen der Ringvorlesung „Nanotechnologie und molekulare Architektur“, Universität Osnabrück, Februar 1999, Stereochemische Interdependenzen - Auf dem Wege zu einem molekularen Motor.

  17. H. Rosemeyer, Frank Seela, XI. International Round Table on Nucleosides, Nucleotides and Nucleic Acids, Leuven, Belgien, 7. – 11. Sept. 1994, Xylose-DNA: Sequence Dependent Duplex Stability as Function of the Backbone Configuration, Poster Abstract Nr. 192 (Poster).

  18. H. Rosemeyer, Frank Seela, XII. International Round Table on Nucleosides, Nucleotides and Nucleic Acids, La Jolla, USA, 15. – 19. Sept. 1996, Steric and Stereoelectronic Effects of Modified Purine Bases on the Sugar Conformation of Nucleosides, Poster Abstract Nr. 56 (Poster).

  19. H. Rosemeyer, Frank Seela, XIII. International Round Table on Nucleosides, Nucleotides and Nucleic Acids, Montpellier, Frankreich, 6. – 10. Sept. 1998, Glycerol - Furcated Oligonucleotides: Synthesis and Aggregation, Poster Abstract Nr. 349 (Poster).

  20. H. Rosemeyer, 7th Ibn Sina International Conference on Pure and Applied Heterocyclic Chemistry, 25. – 28. März 2000, Stereoelectronic Effects of Aza- and Deazapurine Bases on the Sugar Conformation of Nucleosides: Their Relevance for DNA Structure, Invited Lecture.

  21. H. Rosemeyer, Vorträge im Rahmen einer Ringvorlesung im Graduiertenkolleg „Supramolekulare Wechselwirkungen in Nanostrukturen“, November 2001/März 2002.
    a)    NMR-Spektroskopie, 2 Doppelstunden.
    b)    MALDI-TOF Massenspektrometrie, 1 Doppelstunde.

  22. H. Rosemeyer, XI. V. A. Kargin - Vorlesung, Staatsuniversität Tver, 23-25. März 2002. "Frontiers and Perspectives in Nucleic Acid Chemistry", Invited Lecture.

  23. H. Rosemeyer, Frank Seela, XV. International Round Table on Nucleosides, Nucleotides and Nucleic Acids, Leuven, Belgien, 10. – 15. Sept. 2002, Oligonucleotides Incorporating 7-(ϖ-Aminoalkyn-1-yl)-7-deaza-2'-deoxyguanosines: Duplex Stability and Phosphodiester Hydrolysis by Exonucleases (Poster).

  24. H. Rosemeyer, The Purine Heterocycle as Constituent of Natural Products, Rega Institut, KU Leuven, Belgien, 19. Juni 2003, invited lecture.

  25. H. Rosemeyer, The Purine Heterocycle as Constituent of Natural Products, Agricultural University of Warschau, Polen, 3.+ 4. Oktober, 2003, invited lecture.

  26. H. Rosemeyer, The Chemodiversity of Purine as Constituent of Natural Products, 26.02 – 02.03.2004, Al. I. Cuza University, Iasi, Rumänien, invited lecture.

  27. H. Rosemeyer, Supramolecular Stuctures of Nucleolipids, XIII. V. A. Kargin -Vorlesung, Staatsuniversität Tver, 23-25. März 2004, invited lecture.

  28. H. Rosemeyer, Nucleolipids: Natural Occurance, Synthesis, Molecular Recorgnition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials. IV. Romanian International Conference of Chemistry and Chemical Engineering, 21. - 24.9.2005, lecture.

  29. H. Rosemeyer, Nucleolipids: Natural Occurance, Synthesis, Molecular Recorgnition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials. SFB-Statusseminar, Bramsche, Januar 2006.

  30. H. Rosemeyer, Nucleolipids: Natural Occurance, Synthesis, Molecular Recorgnition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials. GDCh-Vortrag TU Braunschweig, 21.01.2006.

  31. H. Rosemeyer, Modified Nucleobases as Potential Inducers of Progenitor-Neuron Transition, Departmental Seminar, Department of Neurobiology, University of Osnabrück, 28.02.2006.

  32. H. Rosemeyer, Nucleolipids: Natural Occurance, Synthesis, Molecular Recorgnition, and Supramolecular Assemblies as Potential Precursors of Life and Bioorganic Materials. Heidelberg-Pharma GmbH, Ladenburg, 02.03.2006.

  33. Helmut Rosemeyer, XVII. International Round Table, Bern, Switzerland, 3. – 7.9.2006. Nucleolipids as Potential Organogelators.

  34. Helmut Rosemeyer, 4th Status Seminar Chemical Biology, DECHEMA, Frankfurt, 26.- 27.11.2007, Hoogsteen Versus Watson Crick Base Pairing: Incorporation of 2-Substituted Adenine- and 7-Deazaadenine 2’-Deoxy-ß-D-ribonucleosides into Oligonucleotides.

  35. Helmut Rosemeyer, Messeauftritt mit eigenem Stand auf dem Gemeinschaftsstand des Landes Niedersachsen auf der Biotechnica 2007, Hannover, 8. – 11. Oktober 2007.

  36. Helmut Rosemeyer, Nucleolipids: Synthesis, Aggregation and Function. III. Nucleinsäurechemietreffen, Universität Stuttgart, 5. September 2008, invited lecture.

  37. Karl Köstler, Helmut Rosemeyer, Building Blocks for the Synthesis of  Oligonucleotides with Hydrophobic Internucleotide Linkage, Annual One-Day Meeting on Medicinal Chemistry, Societe Royale de Chimie and Koninklijke Vlaamse Chemische Vereniging, Katholieke Universiteit Leuven, 7. November 2008. Poster Presentation.

  38. Edith Malecki, Helmut Rosemeyer, Vielberth-Symposium on Nucleic Acids, Regensburg, 10-11.09.2009, Poster Presentation.

  39. Edith Malecki, Helmut Rosemeyer, Symposium on Nucleic Acid Chemistry, Structure and Interactions, Nova Gorica, Slovenia, 31.5. – 2.6.2010,
    Poster Presentation.

  40. Helmut Rosemeyer, Nucleolipide, invited lecture, Universität des Saarlandes, Saarbrücken, 12.10.2011.

  41. Emma Werz, Karl Köstler, Malayko Montilla Martinez, Karsten Gall, Helmut Rosemeyer, VI. Nucleinsäurechemie Treffen, Universität Greifswald, 19. – 20.09.2013, Poster Presentation und Kurzvortrag durch E.W.

Sonstiges

  1. Organisation des internationalen Kongresses "Frontiers of Nucleic Acid Chemistry" 26. November 1999, Hotel Remarque, Osnabrück.